Natural Cancer Treatment in Thunder God Vine Studied in Detroit, Michigan

Cancer – a terrifying diagnosis, a rampant disease and a killer of loved ones world wide.  Cancer knows no mercy, it shows no compassion for our children or our grandparents, our world thought leaders or our beloved neighbor.  And the treatment for cancer, those heralded by the giant pharmaceutical companies and the mainstream medical practitioner is oftentimes as harrowing as the disease itself.

 Thunder God Vine

But it doesn’t have to be.  There are alternatives.

One such alternative cancer treatment is Thunder God Vine.  The studies have been numerous and the results have been very promising – which only validates what practitioners of Chinese medicine have known for centuries.

Thunder god vine (Lei Gong Teng, Thunder Duke Vine, or Tripterygium Wilfordii Hook F) is made of many natural compounds, and two key components are Celastrol and Triptolide, which treat cancer naturally in different ways.  Thunder god vine belongs to a group of plants known as Celastraceae, native to the far east.  The aerial parts of the plant are toxic and can be used as a natural pest control, but the peeled root of the plant holds intense medicinal properties and has been used for centuries by the Chinese to fight cancers, tumors and inflammatory diseases.  Dr. Huanjie Yang at the Barbara Ann Karmanos Cancer Institute in Detroit, Michigan, studies the effects of different Chinese herbs on cancer , and specifically, how different herbs effect the protease complex necessary for the growth of cancer cells.

Cancer cells, according to Dr Yang, require a protease complex in order to grow, as do normal human cells.  However, cancer cells seem more vulnerable to death when protease inhibiting compounds are introduced to the body, causing aptosis (or cell death) of tumor cells much more quickly than normal or non-cancerous cells.

 

Triptolide, one of the primary components of the thunder god root, is a diterpenetriepoxide which inhibits tumor cell growth at low doses and causes tumor cell death at higher doses.

According to Dr. Yang’s study…

  • Triptolide inhibited transactivation of NF-κB induced by Tumor Necrosis Factor-α (TNF-α) and further blocked NF-κB-mediated induction of the inhibitor of apoptosis c- Inhibitor of Apoptosis Protein 1 (IAP1) and c-IAP2.
  • Triptolide inhibited NF-κB transactivation without inhibiting nuclear NF-κB DNA binding activity … or even with increased nuclear NF-κB DNA binding activity.
  • Triptolide inhibited the binding of p65 to transcriptional coactivator CBP/p300.
  • Triptolide also suppressed the phorbolmyristyl acetate (PMA)-induced activation of NF-κB, in turn, inhibited the overexpression of urokinase-type plasminogen activator receptor (uPAR), which is required for tumor cell invasion.
  • In addition, Triptolide inhibited up to 80% mRNA de novo synthesis in various tumor cells by inhibiting RNA polymerase I and II, indicating that it hits a wide spectrum of targets.

 

Celastrol is the secondary compound that was studied by Dr Yang and his team as a derivative of Thunder God Vine.

Celastrol is a quinonemethide triterpene isolated from lei gong teng.  Dr Yang and his team “predicted that celastrol is a proteasome inhibitor by molecular modeling and later confirmed its proteasome-inhibitory activity by in vitro and in vivo experiments” .

Celastrol potently and preferentially inhibits the chymotrypsin-like activity of a purified 20S proteasome with an IC50 value 2.5 μmol/L.  In intact human prostate cancer cells, cellular 26S proteasome was inhibited by celastrol at 1–5 μmol/L. The inhibition of the proteasome activity by celastrol results in accumulation of ubiquitinated proteins and three natural proteasome substrates (IκB-α, Bax and p27), and induction of apoptosis in androgen receptor-positive or androgen receptor-negative prostate cancer cells. Treatment of human prostate tumor-bearing nude mice with celastrol (1–3 mg/kg/day, i.p., for 1 to 31 days) resulted in significant inhibition (65–93%) of the tumor growth. Multiple assays using the animal tumor tissue samples from both early and end time-points demonstrated in vivo inhibition of the proteasomal activity and induction of apoptosis after celastrol treatment. These results demonstrate that celastrol is a natural proteasome inhibitor that has a great potential to be used for cancer prevention and treatment [31].

Celastrol has also been determined to be effective against other types of cancers, such as breast cancer, inhibiting tumor growth effectively by targeting the cysteine 179 in the IκB-α kinase (IKK). Celastrol was able to produce cell death and suppress NF-kB activation, which is a complex in cells that controls the transcription of DNA.  Improper regulation in the body of the NF-kB inhibits the body’s response to infection and inflammation.

According to Dr Yang, Celastrol also…

  • Inhibits Hsp90 by resulting in suppression of its client proteins that play an important role in tumor initiation and progression.
  • Celastrol also suppressed androgen receptor (AR) that mediates signaling important for prostate cancer progression .
  • The aryl hydrocarbon receptor (AhR) is a client protein of Hsp 90, which plays a significant role in polycyclic aromatic hydrocarbon (PAH)-induced carcinogenesis.
  • Celastrol suppressed AhR expression, resulting in decreased transctivation of CYP1A1 and CYP1B1, both of which encode proteins that convert PAH to genotoxic metabolites.
  • Celastrol also inhibited antiangiogenesis by suppressing vascular endothelial growth factor (VEGF) receptors expression.

Does this research mean that Thunder god vine will cure every form of cancer that is out there? No, it does not – but what it does mean is that is can be a viable alternative treatment, and for those who do not want to undergo the chemical warfare that is chemotherapy, this is an alternative treatment method to consider.

References

Yang, Huanjie, Jinbao Liu, and Q. Ping Dou.“Targeting Tumor Proteasome with Traditional Chinese Medicine.” Current Drug Discovery Technologies 7.1 (2010): 46–53. Print.

5 Easy-to-Make Recipes when you’re Travelling Alone

Food is a flexible element of your budget, as you have the greatest control over it. If you’re travelling alone, and on a stringent budget, you can always make your own food with the ingredients available locally. This would not only turn out to be cheap, but would also give you a hands-on feel of the local culture and way of life.

Here are five easy-to-make recipes when you’re travelling alone.

Italy

Italian cities have plenty of things to see and do, and this is why you’ll find all major airlines having flights to Italy. It is the birthplace of most Western comfort foods such as pasta and pizza. While here, you can cook up simple meals with ingredients found in almost every grocery store or supermarket. Pasta is probably the easiest to make. Boil water, add salt, and add pasta to it. Once it cooks, pour some store-bought marinara or white sauce and cook for a few more minutes. Finally, shred your favorite cheese and enjoy. You can add shrimp, chicken pieces, and vegetables also for more variety.

 1 HatM

Source: HatM

 

China

China is growing as a popular destination, and the many flights to China are a testimony to this fact. While here, try the authentic Chinese foods such as Chow Mein. It takes about ten minutes to cook, and you’ll need Chinese noodles, 2 oz pork, 5 oz shrimp, 3 garlic cloves, 1/2 cup shredded cabbage and carrot, soy sauce, water, cooking oil and salt. Cook the Chow Mein first, and then stir fry the veggies, pork and shrimp. Add soy sauce and cook in high heat. Finally, throw in the Chow Mein, and cook thoroughly.

 2 nishikimichuzo

Source: nishikimichuzo

France

France is home to some of the most beautiful places and some amazing food, and this is why there are plenty of flights to France. One easy meal to make here is Capiola Ham and Egg sandwich for which you need bagels, capiola or regular ham, two slices cheese, eggs and some butter. Cut the bagels into two halves and toast them. Pour some butter on a skillet and cook eggs on it to make an omelet. Place a slice of cheese, ham and egg inside the bagels and enjoy!

 3 Alvin Trusty

Source: Alvin Trusty

India

India has some of the most exotic food, so make sure you try cooking here. A simple and staple recipe is stuffed roti, and you can make it with wheat flour, salt, potatoes and cumin. Boil potatoes, peel the skin and mix it with the flour. Add salt, water, oil and cumin seeds, and mix it thoroughly to form a dough. Take small pieces and flatten it out with your hands. Put it on the skillet, and cook it for a delicious meal.

 4 Tasty Indian Food

Source: Tasty Indian Food

Thailand

The many flights to Thailand make it easy to get here, and the local ingredients make it a delight to cook. While here, try the tuna seaweed wrap. Mix about 125 gm flour with water. Heat oil in a skillet and pour a cup of flour on it. Top it with seaweed and cook. Take it out, place some lettuce and tuna in it, and roll it for an easy to carry lunch or dinner.

 5 Mitsooko

Source: Mitsooko

Which of these is your favorite? Do let us know by commenting below.

Know More About Reverse Cell Phone Lookup

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When you get a call and you look at the phone number on your Caller ID and wonder whose number it is, then you need cell phone lookup. This way you would know the name and address of the person calling you. This has been made possible by the reverse cell phone lookup directories available on the Internet.

Typically it is easier to work with reverse phone numbers for landline numbers, but now you can also get information about the mobile phone number owner with the help of reverse cell phone lookup.

There are many reasons why you may need this information. When you are checking Caller ID on your phone at the end of the day, you see a missed call from John Peters fromsome number. Now you wonder who he is and from where he has made this call. Or else you may just find a scrap of paper in your bag or your desk when you are clearing it. There may be a scrawled phone number on it without any name. This means that you just wrote down the number quickly while you were on the phone, or while driving or doing some other chore. But now you donot remember whose number you wrote down. Now either you can find phone owner or just toss away that paper. It may happen that there is a missed call on your cell phone from a number that you donot recognize. Now you need to decide if you should call back, or it was just a sales call or perhaps a wrong number. If you could know who the mobile phone number belongs to, your dilemma will be resolved. In case your physician refers you to a senior doctor or a specialist and gives you that doctor’s name and phone number, you may like to know before calling about where that new doctor is located, and if it will be feasible for you to go there. This is where phone number lookup would have been helpful. Your phone bill may be having a list of several calls that you have made to an unknown number. Now you may have forgotten who you made the calls to, or perhaps they are just an error. This is where you would like to discover phone number owner. This way you can know the importance of this facility!

Benefits Of Using Reverse Phone Lookup

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These are many situations in which reverse cell phone lookup can help you out. It works with a landline number too that is being used for a business or at a residence. Before the advent of the Internet, the phone companies used to publish reverse phone directories. These were also called reverse white pages. They used to be as per a specific town or area and were made available to the police, public libraries and such other places.

It is the speed and convenience of the Internet that brought an end to these paper directories. It has today made phone number lookupas another search engine function. There are a number of options available online today to discoverphone number owner.

There are sites today which provide you with reverse phone lookup. Just go to that siteand type in the phone number. This will let you discoverphone owner. You would be given the person’s name and address.

There are many sites that let you know more about the mobile phone owner. This may be charged unlike the same facility for landline numbers. This is because cell phone numbers are issued by various mobile phone companies and hence the user information is much harder to access. Also, many cell phone users are very keen to treasure their privacy and would not like just anyone to be reaching out to them on their cell phones. But still, there are some cell phone users who would like to find friends and contacts and hence they like to go through reverse phone number lookup. There are many cell phone users who want to know who is calling them when they see any unfamiliar number on their cell phone.

 

Phone number lookup is quite easy. You simply need to go to the site and type in the phone number. You will get the name and address of the phone number owner.

There are a number of reasons you may want this service. Someone may be stalking you or making blank calls or crank calls to you. In this regard you would like to be safe and find phone owner. Or else you may not remember the name of the person whom you have called. In all such cases, you would like to know more about the phone number owner. Hence this facility is of optimum use for such people.

Hairdressers Paignton: Choosing Hairstyle that Suits Your Face

When picking your hairstyle, it is imperative you pick one that suits your face. Your selection should not be influenced by what appeals to you but what actually fits you. Many a time, you will see hairstyles on a celebrity that looks fantastic, but if you copy the same hairstyle, it might not look well on you. Hairdressers Paignton can help you to choose a hairstyle that suits you the most if you take the time to meet with some of them.

But, why is choosing the hairstyle that suits your face necessary? The main reason for this is that all people have different face shapes, and of course, hair texture. This is what most women may overlook when choosing a hairstyle, but it is important to bear this in mind. Of course, there is much that you can do to alter the texture, color, and length of your hair, but changing the shape of your face is something out of your control except you want to go under the knife.

Besides, the style you choose should be able to balance your overall look and your face shape. Having said that, if you choose the right hairstyle that suits your face, it can take away some of the negativities of the face that you may not like. So, the first most important thing you should look at is the shape of your face and what kind of hairstyle will best suit your look.

Another thing to consider is your way of living. Your lifestyle will determine the kind of hairstyle you choose. Some professional hairdressers Paignton can advise you regarding the hairstyle that suits your lifestyle. If you are the type that is on the go frequently, and you just do not seem to have sufficient time for anything else, then you may consider a hairstyle that is going to be quick and easy. For instance, the bob styles or layered cuts may be perfect for your lifestyle. With this hairstyle, there will be no need for much styling. You just need to wash and go. This hairstyle is simple and useful for busy people who do not have much time for their hair.

Also, before you choose your hairstyle, consider your skin tones. And when it comes to coloring for your hairstyles, your skin tone will determine if it looks good on you or not. Seeking the help of hairdressers Paignton is crucial at this stage because they can advise you which will best be suited for your skin tone.

To get the best hairdressers Paignton, go here: www.fortheloveofhair.co.uk

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MGLOBALLY NETWORKER SUMMIT

In simple terms, network marketing is a network of people who have access to a range of products and services that are distributed through that network. Further to this, people can assist in expanding the network by inviting others to join the network, thus extending the concept to their sphere. According to Armstrong Williams, “Networking is an essential part of building wealth”.

And as per Robert Kiyosaki, “The richest people in the world look for and build networks, everyone else looks for work”. In a world of recorded population of 7.4 Billion people, and only 3.5 billion recorded Jobs available, question like ‘can you make money with Multi-Level Marketing?’, will always persist. Even though, today network marketing or Multi-Level marketing has become one of the most popular and sought after technique to introduce new products in the market, some of the Top MLM companies like Amway and rising MLM Companies like MGlobally, which helps you earn money online with Affiliate, struggles a lot on educating people on how they can help them earn Binary income and grow along with them. Countless individuals looking for home based jobs or online jobs have benefitted greatly from MGlobally’s affiliate marketing program and several MLM leaders have endorsed MGlobally’s products and business model. Competing with some of the top MLM companies, MGlobally has garnered a vast global network of sellers who have created a profitable network marketing business for themselves and made their lives extraordinary.

As it is important to educate people on how it is done and create a platform for networkers, MGlobally welcomes you to 2016’s biggest MGlobally networker summit at Dubai where there would be Growth, Magnificence, Party, Energy, thrill and Chill all under one roof. If interested to learn more drop a line at http://goo.gl/qwbB4t. And if you are Not a member, what are you waiting for join now http://goo.gl/7CBOsQ .

Latest Ways to Make Money Working from Home

If you are one of the many people that dread waking up to work on a 9-5 job, and at the same time wishing you could make money working from home, there is good news for you. When it comes to working from home, many people usually turn to the internet as their primary source of making money because truth be told, it is the most reliable way to earn extra income from home. However, before we discuss ways to make money right from home, let us look at what you should avoid if you want to earn money from home.

 

Avoid get rich quick scheme

If you want to make money online, you first need to avoid those get-rich-quick schemes that only get one person rich. This only person will not be you but the schemer. Do not be taken in by the con artist. You certainly do not want to be his next victim. Therefore, you should be willing to put in the time and effort to learn what works, and you will have the opportunity to build a viable business right from your home.

 

Avoid offers that are too good to be true

You might be desperate to get some money, but if you jump at any opportunity that sounds too good to be true, you might hurt yourself. It is imperative to know that the people who are behind these ‘too-good’ scams are very good at what they do. Many unsuspecting and intelligent people have been deceived. They usually present the fraud in such a way that almost anyone will believe them. And when someone is looking for extra income, it is easy to get lulled into these scams. Therefore, you should avoid offers that are too good to be true.

However, there are good ways to make money working from home. Let us examine some simple jobs that can earn you extra income from home.

 

Freelance writing

Years ago, it was difficult working as a freelance writer. But, with the advent of internet technology, working as a freelance writer from home has become easy. There is a huge market for writing. A lot of publishers, website owners, and businesses often need contents. It is an opportunity to grab. You may decide to set up your own website and promote your expertise. Or, you may choose to offer your service on freelance sites like Guru, oDesk, Elance, Fiverr, and similar ones. Ensure you give your best and the job will keep rolling in.

 

Package your knowledge and sell it

Another good way to earn extra income from your home is to sell your skills or knowledge of a particular subject. For example, if you have the cooking knowledge, you might start a recipe class in your home area or package it into an ebook and sell. There are many people who are willing to pay to learn about many fields of knowledge such as gardening, cooking, soap making, to name just a few. Even teaching how to play a musical instrument, do a certain exercise like yoga, or teach foreign languages can all fetch you some money.

 

Rent out free space in your home

This is another way some smart homeowners are using to earn extra income from home. Some travelers need a comfortable place to pass the night other than hotels. So, if you have a spare bedroom and bathroom, you may decide to use this to host people in your home for a specified period. You can make some extra money this way if you have a high tolerance for other people being in your home.

If your home is in a fine location, you can set aside space for this purpose. Also, you should set up a website to promote it locally, and those travelers who need a place to stay will be able to find your home upon search. You may also decide to promote your service on a site like Airbnb.

 

Sell your creativity online

 If you have the gift of creating beautiful things, then this could be an excellent opportunity for you to make some serious dough from home. The growing trend for creative and attractive homemade products shows no signs of stopping, and the Internet presents an excellent avenue to market your creativity. There are some online outlets like Etsy where you can easily sell your creativity. So, if you have got some creative ability, why not use it to make money working from home?

To learn more about making money online, go here: www.makemoneyonlinemagic.com

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